Meeting the demand for safe and adequate supplies of water, especially in regions undergoing hotter and drier weather conditions, requires addressing research gaps associated with water reuse and water storage, including enhanced or managed aquifer recharge. Sustainable and safe water supply is a common theme for states and communities across the nation. Key research needs include chemical and microbial risk assessments for fit for purpose reuse, treatment characterization and performance as well as reliable supplies and cost, which will assist communities in their water reuse and aquifer recharge decisions. This webinar will provide an overview of ongoing EPA ORD research related to alternative water sources including decentralized water reuse, protein processing plants, treated produced water from oil and gas activities, and enhanced/managed aquifer recharge, as well as collaborations with our partners.